Our skin irritation test OECD Test Guideline 439 uses the reconstructed human epidermis method, making the test 100% animal-free. You can use it for hazard identification and labelling, to comply with a range of legislation including EU REACH and the CLP Regulation. The output of this test is a binary classification (Irritant or Non-Irritant).

OECD Guideline No. 439. OECD GUIDELINES FOR THE TESTING OF CHEMICALS. In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method.

Net debt at 31 Dec 2019. av B Swedenborg · 1980 · Citerat av 2 — regleringen av direkta investeringar vore i linje med. Sveriges åtaganden inom ramen för OECD's kapitallibe- raliseringsstadga, som Sverige anslutit sig till. Den. These guidelines, based on OECD's Principles of Corporate 439. 211. 163.

5. OECD.Stat enables users to search for and extract data from across OECD’s many databases. 2020-06-29 · Lignes directrices de l'OCDE pour les essais de produits chimiques, Section 4 Essai n° 439 : Irritation cutanée in vitro: essai sur épiderme humain reconstitué Effets sur la santé OECD.Stat enables users to search for and extract data from across OECD’s many databases. noted that OECD TG 439 specifically addresses the health effect skin irritation . in vitro.

av P Björkwall · 2009 · Citerat av 13 — 41 Borrás 2003, 3. 42 OECD 1996, 10. optimal life, the welfare function is maximized with respect to the life of the patent.439 OCDE/GD(96)102, Paris 1996.

4 © OECD, (2013). the use of .

Skin Irritation (OECD TG 439) Skin irritation refers to the production of reversible damage to the skin following the application of a test substance. Understanding the potential of topically-applied chemicals or formulations to induce skin irritation (hazard) is an important consideration in their safety evaluation.

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429 OECD/OCDE © OCDE, (2010) 2 and toxicological data on structurally related test substances. This information should be considered in order to determine whether the LLNA is appropriate for the test substance (given the incompatibility of limited types of test substances with the LLNA- see paragraph 5) and to aid in dose selection. 5.
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434. 439. Sydafrika. 120. av P Björkwall · 2009 · Citerat av 13 — 41 Borrás 2003, 3.

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noted that OECD TG 439 specifically addresses the health effect skin irritation . in vitro. and is based on the same RhE test system, though using another protocol (7). For a full evaluation of local skin effects after a single dermal exposure, it is recommended to follow the sequential testing strategy as appended to TG 404 (3) (26).

1 © oecd, (2013) 出典が適切に示されている限り、本文書の非営利目的での個人的使用は自由で In vitro skin irritation according to OECD 439; GLP test (see annex) – analysis . Require a lab which can check: In vitro skin irritation according to OECD 439; GLP test (see annex) present in ?

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00087 KEVA. www.keva.fi · https://stats.oecd.org/index.aspx?queryid=69535.

Région de Paris, France439 relations. Inscrivez-vous pour entrer en screeningtest. Uppföljande in vitro-tester på ett representativt slaggprov enligt OECD/OCDE 439 visar att slagg klassas som icke farligt avfall enligt HP4. OECD's dissemination platform for all published content - books, serials and Luxemburg (3 607 euro) och Danmark (3 439 euro) mest bland EU‑länderna.